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Recent Department Publications, Presentations, Grants, Instrument Purchases, and News.
March 2010: Corinne Deibel, Paul Ogren and Lori Watson attended the 239th American Chemical Society National Meeting in San Francisco with ten Chemistry and Biochemistry Earlham students who presented their student-faculty collaborative research projects in the Undergraduate Research Session. Funding for travel was supported in part by the Earlham Ford/Knight Fund and a grant from the W.M. Keck Foundation. Presentations included:
January 2010: Earlham College Chemistry Alum (EC 1965) and Distinguished Professor of Chemistry at the University of California, Irvine, Larry E. Overman has been awarded the Herbert C. Brown Award for Creative Research in Synthetic Research. The award recognizes outstanding and creative contributions to research in synthetic methods. In addition to having the distinction among organic chemists of having a reaction named after him (the Overman rearrangement), Overman has more than 340 publications, which includes the total synthesis of more than 80 natural products. Together with his brother Jack Overman who also attended Earlham, Larry has endowed a scholarship (The Dorothy Riggin Overman and Lemoine Overman Scholarship Fund) to be awarded annually to an outstanding Earlham College chemistry student in their sophomore, junior, or senior year. This scholarship will support summer research activity of the student (stipend and supplies), or provide tuition support for the student awardee during the academic year.
October 2009: Four students and their faculty mentors (Mark Stocksdale and Kalani Seu) presented posters at the Undergraduate American Chemical Society Poster Session held at Dow AgroSciences in Indianapolis. Posters included:
July 2009: Congratulations to Lori Watson, Assistant Professor of Chemistry, who was a co-author on a paper entitledJCE VIPEr: An Inorganic Teaching and Learning Community in the Journal of Chemical Education.
April 2009: Congratulations to emeritus Professor of Chemistry Paul Ogren, who was a co-author on a paper entitled "The Limit of Detection in Generalized Least-Squares Calibrations: An Example Using Alprazolam Liquid Chromatography-Tandem Mass Spectrometry Data" in the Journal of Analytical Toxicology.
April 2009: Four biochemistry majors presented their Earlham research at the 21st Annual Butler University Undergraduate Research Conference on Friday, April 17, 2009. Victor Anciano presented a poster, "The Expression of Heat Shock Protein 70 and Metallothionein in Trout Red Blood Cells Exposed to Cadmium." Chris Owens and Juan Hernandez presented a poster, "The Expression of Metallothionein I in Indiana Game Fish Exposed to Copper." Both of these were summer experiences supported by the WM Keck Foundation grant. Leo Bautista gave a talk entitled "The Expression and Activity of Aromatase in Canine Reproductive Tissues" which was a culmination of the laboratory in Chemistry 351, Biochemistry, Fall, 2008.
March 2009: Congratulations to Lori Watson, Assistant Professor of Chemistry, who presented a talk at the American Chemical Society National meeting, Salt Lake City, UT: "VIPEr: A resource and community for teaching inorganic chemistry" and a poster: "VIPEr:the Virtual Interactive Pedagogical Electronic Resource".
January 2009: Congratulations to Lori Watson, Assistant Professor of Chemistry, who was a co-author on a paper entitled IONiC: A Cyber-Enabled Community of Practice for Improving Inorganic Chemical Education in the Journal of Chemical Education
December 2008: An image of a canine ovarian follicle expressing the enzyme aromatase as detected by immunohistochemistry has been published by Abcam, an antibody/biotech firm. The image was created by students in Chemistry 351, Biochemistry, Fall, 2008.
October 2008: 22 posters were presented at the 2008 Earlham College Science Division Undergraduate Research Poster Conference, including 13 posters from Chemistry and Biology/Chemistry students. See their abstracts here.
October 2008: Ten chemistry and biochemistry students presented research performed with their faculty mentors (Mike Deibel, Corinne Deibel, Paul Ogren, Mark Stocksdale, and Lori Watson) at the annual Undergraduate American Chemical Society poster Session held this October at Ball State University in Muncie, IN. The students presented the research carried out last summer in the Chemistry Department. Presentations included:
September 2008: Congratulations to emeritus professor Paul Ogren who is an article co-author on "The Limit of Detection in Generalized Least-Squares Calibration: An Example using Alprazolam LC/MS/MS Data" accepted for the Journal of Analytical Toxicology.
July 2008: Congratulations to Lori Watson, Assistant Professor of Chemistry, who co-presented a workshop at the 20th Biennial Conference on Chemical Education, Bloomington, IN: "Introduction to the Chemical Education Digital Library."
June 2008: Kudos to emeritus professor Paul Ogren who is an article co-author on "Comparison of Ordinary, Weighted and Generalized Least-Squares Straight-Line Calibrations for LC/MS/MS, GC/MS, HPLC, GC and Enzymatic Assay" published in the Journal of Analytical Toxicology(2008, 32, 329-338).
May 2008: Congratulations to Lori Watson, Assistant Professor of Chemistry, who was a co-author on a paper entitled "IONiC: A Cyber-Enabled Community of Practice for Improving Inorganic Chemical Education" presented at the ConfChem Conference [Online] April-June 2008.
April 2008: Congratulations to Lori Watson, Assistant Professor of Chemistry, who presented a talk at the American Chemical Society National meeting, New Orleans, LA: "Integration of research experiences into the introductory chemistry curriculum: A collaborative multidisciplinary model investigating metal contamination of a local watershed" and a poster: "IONiC: Interactive online network of inorganic chemists."
November 2007: Congratulations to Lori Watson, Assistant Professor of Chemistry, who was part of a group of inorganic chemistry faculty from seven schools to be awarded a $150,000 grant from the National Science Foundation: "IONiC: A Cyber-Enabled Community of Practice for Improving Inorganic Chemical Education."
October 2007: Congratulations to Michael Deibel, associate professor of chemistry, who presented a talk at the October Earlham Forum: "Monitoring Local Watersheds," a report on the W. M. Keck Foundation grant to research and develop curriculum modules investigating metal contamination in local watersheds. October 2007: During mid-term break, Corinne Deibel, Mark Stocksdale and Lori Watson accompanied ten chemistry and biochemistry students to the Undergraduate ACS poster Session at Eli Lilly in Indianapolis. The students presented the research carried out last summer in the Chemistry Department. Here is a listing of topics and presenters:
Progress Toward the Total Synthesis of Avenic Acid and Related Analogs, Alexander W. Cogbill, Whitney E. England and Mark G. Stocksdale. • Further Studies of Tungsten Oxo-Imido Complexes with N-heterocyclic Carbene Ligands, David R. Cabrera, Carly Z. Smith and Lori A. Watson. • Development of a New Environmental Chemistry Module for the General Chemistry Laboratory, Razan E. Issed, Kyle B. Edwards and Corinne C. Deibel. • Analysis of Trace Metal Concentrations in Water and Sediment Core Samples from Springwood Lake, Martin K. Gachoro, Kate Skog, and Michael A. Deibel. • Ethnobotany: A Brief Study of Historical Herbal Remedies and Medicines in the Mid-West, Sharif Qaddomi and Mark G. Stocksdale. • Beta3-Peptides That Form 14-Helices by Incorporation of Cation-Pi; Interactions, Damian Almiron, Janny Concha Urday Zaa, John Klyce and Olen Stephens. • Regulation of the Forkhead transcription Factor Foxo3a by Protein Phosphotase 2A, Shaden Khalaf, Amrik Singh and Roya Khosravi-Far.• Pharmaceuticals, Then and Now: a Living History of Medicines and Drugs, Lindsey V. Howlett, Manuel Myers and Mark G. Stocksdale.
September 2007: Congratulations to Associate Professor of Chemistry Mark Stocksdale who has received a $99,998 grant from the U.S. Department of Agriculture (USDA). Funding for this competitive grant proposal, Uptake Specificity of Synthetic Phytosiderophore Analogs by Graminaceous Plants, is the first Earlham has received from the USDA.
September 2007: Congratulations to Assistant Professor of Chemistry Lori Watson who has recently published two articles: "Operationally Unsaturated Pincer/Rhenium Complexes Form Metal Carbenes from Cycloalkenes and Metal Carbynes from Alkanes." Journal of the American Chemical Society, 2007, 129(18), 6003-6016 and "Bis(methylidene) Complex of Tantalum Supported by a PNP Ligand." Organometallics, 2007, 26(20), 4866-4868. August 2007: Congratulations to Mark Stocksdale, associate professor of chemistry, and Margaret (Midge) Padgitt '07 who were coauthors on a recently published paper: "(S)-(2,2-Dimethyl-5-oxo-1,3-dioxolan-4-yl)acetic acid," Acta Crystallographica, 2007, E63, o3767-o3768. This article is Midge's first peer-reviewed publication; if you know Midge, send her congratulations! April 2007: Corinne and Mike Deibel, Mark Stocksdale, Lori Watson and Paul Ogren accompanied nine chemistry and biochemistry students to the National Meeting of the ACS in Chicago. The students presented the research carried out last summer in the chemistry department. Here is a listing of topics and presenters:
February 2007: Kudos to Mike and Corinne Deibel and Lori Watson, of the Earlham Chemistry Department, for their role in obtaining a $360,000 grant from the W.M. Keck Foundation along with colleagues in Biology, Geosciences, Mathematics, and Computer Science for undergraduate interdisciplinary research.
January 2007: Kudos to Mark Stocksdale, Associate Professor of Chemistry, who was published this month as co-author of "Synthesis and Evaluation of Antitumor Activity of Novel N-Acyllavendamycin Analogues and Quinoline-5, 8-diones," in Bioorganic & Medicinal Chemistry (2007, 15, 495-510).
October 2006: Earlham College and the Chemistry Department were the proud hosts of the 7th Annual Indiana Local Section American Chemical Society Poster Session on October 10, 2006. Approximately 125 undergraduates, faculty members, industrial chemists, and other chemistry aficionados from ten regional colleges/universities and three chemical corporations attended the event. Representing Earlham College were:
• Student Justin Colanese and faculty member Michael Deibel presenting "Antioxidant Activity In Herbal Extracts And Isolated Fractions" • Students Rachel Stacy and Alex Graham with faculty member Corinne Deibel presenting "GC/MS/MS Analysis Of Atrazine And Three Metabolites Using Chemical Ionization And Multiple Reaction Monitoring" • Student Gaya Hettiarachchi and faculty member Lori Watson presenting "Progress Toward The Syntehsis of Tugsten, Rhenium, and Molybedenum Bisimido Complexes Using 1,4-Di-Tert-Butyl-1,4-Diazabuta-1,3-Diene (DAD)" • Students Felicia Gray and Liz Yoder with faculty member Lori Watson presenting "Rhenium And Tugsten Oxo And Imido Complexes With N-Heterocyclic Carbenes" • Students Logan Giles and Paul Durand with faculty member Lori Watson presenting "Toward The Synthesis of Rhenium Imido Complexes Using 1,3-Diaminobenzene" • Students Alan O'Connor, Rob Kinne, and Matt Peoples with faculty member Mark Stocksdale presenting "Synthesis of Labeled Phytosiderophore Analogs" • Student Matt Peoples presenting his research "Purification and Characterization of Recombinant Aequeorea coerulescens Green Fluorescent Protein from Escherichia coli" • Student Kushboo Goel presenting her research "Tagging of Photosstem 1 With Green Fluorescent Protein For Its Identification In Mammaliam Cell Membranes", performed at Oak Ridge National Lab during a semester-long research experience.
June 2006: We received our new PerkinElmer AAnalyst 800 series Atomic Absorption Spectrometer!
May 2006: We, the faculty and students of the Chemistry Department, would like to honor Paul J. Ogren for his 27 years of service to Earlham College and our department. Paul graduated Earlham College in 1963, received his Ph.D. in Physical Chemistry at the University of Wisconsin, Madison in 1969, and returned to teach at Earlham in 1979. Since then, he has taught countless students in courses such as General Chemistry, Equilibrium and Analysis, Thermodynamics and Kinetics, and Quantum Chemistry. Although Earlham professors focus foremost on undergraduate education, Paul has found time to publish many peer-reviewed articles in national journals of chemistry and chemical education. Over the years, Paul has taught glassblowing, one of his personal hobbies, to small groups of students. He also keeps many of the department instruments in working order, and we hope he shares that expertise before embarking on a well-deserved vacation! Happy retirement, Paul!
Paul's position in the Chemistry Department will be filled by Lori Watson, Assistant Professor of Chemistry. Lori's research interests are in inorganic chemistry, catalyst chemistry, and computational chemistry. She received her Ph.D. in Inorganic Chemistry from Indiana University in 2004.
April 2006: Kudos to Paul Ogren, as well as all of the Chemistry faculty, for hosting a successful and fun Spring Picnic at the Ogren's. Approximately 25 Chemistry and Biochemistry majors / prospective majors from across all four class years attended. Thanks, professors, for making our department the best (and best-fed) on campus! - EC students
January 2006: Kudos to Mark Stocksdale, Associate Professor of Chemistry, who was co-author of the recently published paper "Novel Lavendamycin Analogues as Antitumor Agents: Synthesis, in Vitro Cytotoxicity, Structure-Metabolism, and Computational Molecular Modeling Studies with NAD(P)H:Quinone Oxidoreductase 1," in the Journal of Medicinal Chemistry, 2005, 48, 7733-7749.
October 2005: Eight students and four faculty members ventured to Dow Agrosciences in Indianapolis, Indiana, to present their research at the 6th Annual Indiana Local Section of the American Chemical Society Poster Session. Congratuations to all students (indicated by an asterisk) and faculty!
• Kate M. Skog*, Lori A. Watson: Progress towards the synthesis of rhenium 1,2-di(di-tert-butylsilylamine) benzene trichloride and the synthesis of rhenium trans-1,2-diamino cyclohexane trichloride. • Phoebe Richgels*, Corinne C. Deibel, and Paul J. Ogren: Investigation of tadpoles exposure to atrazine and its metabolites. • Janee' A. Bryant*, Lori A. Watson: Toward the synthesis of a constrained geometry bissilyl imide ligand. • Nathaniel Bass*, Lori A. Watson: Using density functional theory to predict competitive activation of N-C and C-H bonds of a PNP framework by monovalent rhodium. • Robert J. Kinne*, Matthew S. Peoples*, Douglas A. Hardesty*, and Mark G. Stocksdale: Progress towards novel phytosiderophore analogs. • Pachi A. Rogriguez*, Kari A. Wilder-Romans*, and Paul J. Ogren: Analysis of environmental mercury with an improved gold trap - fast release - cold vapor fluorescense method.
September 2005: The Chemistry Department has purchased a new Gas Chromatograph/Mass Spectrometer! This instrument purchase was made possible by a grant awarded from the Borman Family Foundation. (Stocksdale, M. G., Deibel, M. A., Deibel, C., Ogren P. J., Watson, L. A., "Acquisition of a Gas Chromatograph-Mass Spectrometer for Use in Undergraduate Research and Teaching Laboratories.") The Varian 2200 series GC/MS has recently arrived and been installed in the department.
July 2005: The Camille and Henry Dreyfus Foundation has awarded Assistant Professor of Chemistry Lori Watson a $30,000 grant for her proposal entitled "Reactivity of unsaturated bisimido, phosphinoimido, and phosphineoxoimido transition metal complexes toward alkene metathesis, hydrogenation and C-X bond activation." This money will go towards stipends for undergraduate summer researchers, chemical supplies, and travel expenses for faculty-student presentations at national meetings.
Summer 2005: The Chemistry Department has purchased an MBraun Unilab inert-atmosphere glovebox! This new equipment will be of great use in dealing with highly reactive compounds. See installation pictures.
April 2005: Kudos to Mike Deibel, on sabbatical this semester, who was co-author of "Quantitative Thin-Layer Chromatography/Mass Spectrometry Analysis of Caffeine Using a Surface Sampling Probe Electrospray Ionization Tandem Mass Spectrometry System," accepted for publication this month in Analytical Chemistry.
April 2005: Kudos to Lori Watson, Assistant Professor of Chemistry, who was co-author of "Four-Coordinate Titanium Alkylidene Complexes: Synthesis, Reactivity, and Kinetic Studies Involving the Terminal Neopentylidene Functionality," published in this month's Organometallics (24, 1886).
March 2005: Professors Mark Stocksdale and Lori Watson accompanied students Adair Lindsay ('06), Rachel Stacy ('07), and Doug Hardesty ('07) to the 229th National Meeting of the American Chemical Society in San Diego, California. There, Rachel presented her research entitled "Polymer-Bound Ph3P in Mitsunobu Reactions Involving Cyclic beta-Hydroxy Tertiary Amines," while Adair and Doug presented their organic synthesis research entitled "Synthetic Efforts Toward Novel Phytosiderophore Conjugates."
March 2005: Kudos to Mike Deibel, on sabbatical at Oak Ridge National Laboratory, who was co-author of "Thin-Layer Chromatography and Mass Spectrometry Coupled Using Desorption Electrospray Ionization," published in this month's Analytical Chemistry (77, 1207).
January 2005: Kudos to Lori Watson, Assistant Professor of Chemistry, who was co-author of "Decarbonylation of Acetone and Carbonate at a Pincer-Ligated Ru Center," published this month in Organometallics (24, 186).